Filling unit with a “2 in 1” filling head with two filling adaptors. One to fill from 1 to 30 Kg with high accuracy and for medium-low outputs (large cans) and a second one to fill from 5 to 30, Kgs,
Shanghai Guangzhi Gravimetric Fillers conquer density/temperature/viscosity variables with ±0.05% mass accuracy – outperforming volumetric systems by 300% in precision. Engineered with OIML Class 0.5 load cells, real-time AI density compensation, and GMP/ATEX-ready construction, they eliminate foam/bubble errors, thermal drift, and recipe-change waste for vaccines, solvents, and high-value adhesives.
1. Mass-Metering Science
| Component | Technology | Performance |
|---|---|---|
| Multi-Cell Load Array | 4× OIML R60 Class 0.5 load cells | ±0.02% linearity error |
| Loss-in-Weight Control | Predictive flow algorithm | ±0.05% setpoint accuracy |
| AI Density Compensation | Auto-adjusts for ±20% SG shifts | 10ms response time |
| Seismic Rejection | Active vibration damping | 95% floor vibration rejection |
2. Zero-Waste Architecture
Critical Features:
Smart Dribble Control: 100 L/min → 0.5 L/min transition
Overfill Prevention: Dual-cutoff (load cell + timer)
Static Dissipation: Conductive paths <10? Ω
3. Material-Specific Engineering
| Challenge | Guangzhi Solution |
|---|---|
| Foaming Liquids | Vacuum-assisted filling |
| Aerated Sauces | Pulsed-pressure filling |
| Shear-Sensitive mAbs | Low-shear peristaltic dosing |
| Static-Prone Solvents | Ionizing bars + grounding verification |
| Model | Pharma Micro-Filler | Industrial Macro-Filler | ATEX Chemical Filler |
|---|---|---|---|
| Capacity Range | 1g-5kg (±0.02%) | 1-100kg (±0.05%) | 5-1000kg (±0.1%) |
| Throughput | 200 fills/hour | 500 fills/hour | 300 fills/hour |
| Max Density Shift | ±15% compensated | ±20% compensated | ±15% compensated |
| Container Types | Vials/cartridges | Pails/drums | IBCs/ISO tanks |
| Material Contact | 316L EP + USP VI | 316L + PTFE | Hastelloy C276 |
| Power | 110V/0.5kW | 380V/3.5kW | 24VDC Ex ia |
| Calibration | Auto-span with NIST wts | Semi-auto calibration | Remote calibration |
| Footprint (L×W×H) | 1000×800×1500mm | 2500×1200×2200mm | 3000×1500×2500mm |
Pharmaceuticals
21 CFR Part 11 electronic records
Isolator integration (ISO Class 5)
Single-use flow path option
Food & Sauces
USDA-compliant materials
Allergen purge protocol
CIP at 85°C
Chemicals & Solvents
ATEX Zone 1/21 certification
Vapor recovery >99%
Static control (<10? Ω)
Cosmetics
Perfume alcohol compatibility
Anti-foam pulsed filling
10" HMI with AI Process Optimizer
Key Modules:
OEE Dashboard:
Material consumption vs target
Vibration interference alerts
Energy per fill (kWh/kg)
Self-Diagnostics:
Load cell drift detection
Filter clogging prediction
Global Vaccine Manufacturer:
Challenge: ±3% fill variation in lipid nanoparticles (density shifts)
Solution: Gravimetric filler with AI density compensation
Results:
? ±0.08% accuracy for $500k/L materials
? Zero batch rejection in 12 months
? ROI: 3 months
Global Compliance:
OIML R60 Class 0.5
FDA 21 CFR 210/211
ATEX 2014/34/EU (Zone 1)
ISO 9001:2015
Advanced Modules:
| Module | Function |
|---|---|
| Inline Rheometer | Real-time viscosity (±2 cP) |
| Robotic Taring | Auto-container weight learning |
| AR Maintenance Guide | HoloLens-assisted calibration |
| Carbon Tracker | kg CO? per tonne filled analytics |
24/7 Metrology Support:
Remote diagnostics via IIoT gateway
Critical Spares Dispatch ≤48h:
Load cells (OIML Class 0.5)
Dribble valves
Vibration dampers
Performance Validation:
NIST-traceable weight certification
Material adhesion optimization
Where Every Milligram Matters
Shanghai Guangzhi Gravimetric Fillers: Engineering absolute precision for the world’s most valuable fluids – from vaccines to nano-suspensions. ??
